The ancient Near East refers to early civilizations in a region roughly corresponding to the modern Middle East: Mesopotamia (modern Iraq and Syria), Anatolia (modern Turkey), the Levant (modern Syria, Lebanon, Israel, Palestine, and Jordan), as well as Persia (modern Iran), and Ancient Egypt, from the beginnings of Sumer in the 6th millennium BCE until the region's conquest by Alexander the Great in the 4th century BCE.