A translator of Aristotle and friend of Jacob of Edessa and Athanasios of Balad, George, Bishop of the Arab Tribes (d. AD 724) was an important figure in the history of the life and thought of the Syrian Orthodox Church. As Bishop over bilingual Christian Arab tribes in the Umayyad period, George is also significant for understanding the intellectual spectrum of the late seventh and early eighth century Near East. George has, however, received comparatively little scholarly attention. This article attempts to help to rectify this deficiency by offering a study of the first three of George’s eleven extant letters and relating them to the larger Christian and Islamic context of his day. It will be of interest to students of Greek patristics, Syriac Christianity, and early Islamic history.